Browsing by Author "Wanasinghe, AT"

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    Design and analysis of a mems based transdermal drug delivery system
    (IEEE, 2020-07) Perera, KNM; Awantha, WVI; Wanasinghe, AT; Herath, HMDP; Paththinige, SSHG; Ekanayaka, L; Amarasinghe, YWR; Weeraddana, C; Edussooriya, CUS; Abeysooriya, RP
    The design and analysis of a Micro Electromechanical System-based (MEMS-based) Transdermal Drug Delivery System are presented in the research article. A conceptual design for the delivery of Levodopa was proposed by the authors. Major components of the system were identified as a microfluidic pump, microneedle array and the microfluidic channels connecting the system. The working principles of these components were selected according to the persisting requirements and design considerations. Simulations were conducted to evaluate the performance and to optimize the design of the system. A fabrication method for the system was proposed by the authors as a stacked layer. The results of the simulations conducted were presented. The simulations show positive results with the performance of the system and do not suggest a mode of mechanical failure of the system at the given boundary conditions. The paper concludes with recommendations for future work.
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    Evaluation of hand tremor frequency among patients in Sri Lanka using a soft glove
    (IEEE, 2020-07) Kavindya, P; Awantha, WVI; Wanasinghe, AT; Kulasekera, AL; Chathuranga, DS; Senanayake, B; Weeraddana, C; Edussooriya, CUS; Abeysooriya, RP
    Tremors are the involuntary oscillations of a body part which occur due to diseases such as Parkinson’s Disease (PD), Essential tremor (ET) or stroke, which disturbs the activities of daily living (ADL). This paper presents an evaluation of hand tremor frequency among patients in Sri Lanka using a soft glove embedded with inertial measuring units (IMU) and its development and validation. This is a research towards the development of a hand tremor suppression device which requires data on hand tremors. To the best of the authors’ knowledge, no local data is available on hand tremors despite the availability of global studies. The hand tremor was quantitatively analyzed and the dominant frequency for each patient, overall mean and standard deviation of peak frequencies were obtained for this study group. The results show a mean of 5.05 ± 2.03 Hz for peak frequencies for the hand tremor patient sample in Sri Lanka. By the gender 4.62 ± 1.78 Hz and 5.69 Hz ± 2.38 Hz are the mean of peak frequencies for male and female sample respectively. This research will also be useful in disease diagnosing in clinical studies and developing hand tremor assessment tools.